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  • Full-Field Cell Morphology
  • September 9, 2026

Digitize Bone Marrow Review for 46% Faster Cell Analysis

Bone marrow aspirate review is one of the most demanding workflows in hematopathology. Cases involve multiple slides per patient, require expert interpretation, and traditionally depend on a hematopathologist being physically present at a microscope.

Scopio's Full-Field Bone Marrow Aspirate™ Application removes that dependency. Running on the Scopio X100 and X100HT scanners, it captures the aspirate at true 100x oil-immersion-equivalent resolution in one continuous digital view - then layers AI-powered cell pre-classification on top, so experts spend their time interpreting rather than counting.

In a prospective time-and-motion study, the digital workflow delivered 46% faster cell analysis and eliminated an average of 139 head and neck movements per review.¹

What is Full-Field imaging?

Full-Field is Scopio's proprietary imaging technology. Conventional digital microscopy forces a tradeoff between resolution and field of view - you get cellular detail or spatial context, not both. Using computational photography, Full-Field captures true 100x oil-immersion-equivalent resolution across large areas or the entire slide in a single continuous digital view.

The practical result: you move from single-cell detail to a macro view of the whole sample the way you would at a microscope, but entirely on screen - without piecing together fragmented cell snapshots.

Three things that change on day one

Dynamic, Full-Field digital review

Continuous 100x imaging lets you transition instantly between single-cell resolution and the full-slide macro view. Navigate the sample as you would on a microscope, with none of the mental load of reassembling fragmented snapshots.

Half the manual effort

Automated pre-classification across 17 nucleated cell classes, drawn from thousands of analysed cells, delivers a standardized review across every shift and every site - reducing the burden of manual differentials.

Sign off from anywhere*

Browser-based access, DICOM image export, and LIS integration connect bone marrow review to your existing digital pathology ecosystem. Consult with peers and sign off on any case, from any location on the secure network. No slide transport required.

The workflow, end to end

  1. Load slides to scanner - intuitive loading, minimal training
  2. Select scan mode - whole slide imaging, automated, or user-defined area selection
  3. Full-Field scanning - continuous 100x capture
  4. AI-powered nucleated cell differential - pre-classification across 17 classes
  5. Review, confirm, and consult - expert retains full diagnostic authority
  6. Report and export - HL7 report plus DICOM image export

Key capabilities

  • Flexible scan modes - from targeted area to Whole Slide Imaging (WSI)
  • Multi-slide case handling - merge multiple slides per patient into a single consolidated case
  • Automated specimen quality assessment - particle presence, precursor cell presence, overall specimen quality
  • Cell detection and pre-classification - AI pre-classifies nucleated cells into 17 classes
  • M:E ratio calculation - automated myeloid-to-erythroid ratio from classified cell populations
  • Megakaryocyte identification - slide-wide detection
  • Abnormal cell tagging - mark cells as abnormal during review and calculate the percentage within each cell class, supporting dysplasia assessment
  • Flexible analysis area management - accept AI-suggested areas or add your own
  • Annotation tools - flag clinically significant cells and areas for second opinion or the final report
  • Extended color compatibility - broad range of color configurations across diverse staining protocols
  • DICOM image export - long-term archiving and integration with existing digital pathology infrastructure
  • Remote review and collaboration - browser-based access from anywhere on the secure network, no dedicated software

Frequently asked questions

Slides are loaded into a Scopio X100 or X100HT scanner and captured at 100x resolution using Full-Field imaging. AI detects and pre-classifies nucleated cells into 17 classes and calculates the M:E ratio. The hematopathologist then reviews, adjusts, and confirms every result in a browser, before signing off and exporting an HL7 report with DICOM images.

A prospective time-and-motion study found 46% faster cell analysis compared with the manual workflow, and eliminated an average of 139 head and neck movements per review.¹

17 nucleated cell classes, plus slide-wide megakaryocyte detection. Classification is pre-classification only - the expert verifies every result and retains full diagnostic authority.

Yes. Review, consultation, and sign-off run in a standard browser from anywhere on the hospital's secure network. No dedicated software and no slide transport.

Yes. Scan modes range from targeted analysis areas to full Whole Slide Imaging of the entire aspirate slide.

Romanowsky stains with AI decision support, and Prussian Blue without AI decision support. A broad range of color configurations supports diverse staining protocols.

Yes - bi-directional LIS integration via HL7, and native DICOM image export for long-term archiving.

Ready to modernize your bone marrow workflow?

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¹ Prospective time-and-motion study. Pabon E. et al., Beckman Coulter Diagnostics, 2026.

*Scopio's Full-Field Bone Marrow Aspirate Application is CE-marked and cleared for sale in CE countries as well as in additional regions. Pending FDA clearance in the US.

*Remote review is available via the hospital's secure network.